Journal of Ultrafine Grained and Nanostructured Materials

Journal of Ultrafine Grained and Nanostructured Materials

Advances in nanocarriers as drug delivery systems in Atherosclerosis therapy

Document Type : Review Paper

Authors
Shadi Motamed
Seyed Nasir Hosseini Karimi
Mohammadreza Hooshyar
Rouhollah Mehdinavaz Aghdam
School of Metallurgy and Materials Engineering, College of Engineering, University of Tehran, Tehran, Iran.
10.22059/jufgnsm.2021.02.09
Abstract
Cardiovascular diseases (CVDs) are known as killer diseases and to overcome these diseases, novel approaches are needed. Although many approaches were able to control this disease, they still had high risks for the patients. One of the best ways to control CVDs is to use targeted Nanosystems, with the help of Nanotechnology and Biology Sciences. Despite current therapeutic strategies to reduce risk, patients still experience the consequences of CVD. Improve visualization of early atherosclerotic lesions to decrease residual CVD risk is one of its goals. Nanomaterials used as Nanocarriers are mainly Polymeric based, Magnetic, Metalic, Silica based and Liposomes. In addition, some drugs can be loaded to these Nanocarries. In this review, we focused on nanocarriers to manage Atherosclerosis, which is the most prevalent type of CVD. We divided these nanocarriers into five main groups: Polymeric nanocarriers, Magnetic nanocarriers, Metalic nanocarriers, Liposomes and Silica-based nanocarriers.
Keywords
Atherosclerosis
Targeted therapy
Nanocarriers
Polymeric nanocarriers
Magnetic nanocarriers
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Journal of Ultrafine Grained and Nanostructured Materials
Volume 54, Issue 2
December 2021
Pages 198-210

  • Receive Date 04 April 2021
  • Revise Date 01 August 2021
  • Accept Date 28 August 2021